Aug
25
Doping Screening For Winstrol | Stanozolol
August 25, 2006 |
Stanozolol is better known under the name Winstrol. Initially it was developed by Winthrop Laboratories in 1962. It is a synthetic anabolic steroid derived from testosterone, and has been approved by the FDA for human use.
Stanozolol can be used in bodybuilding, typically “stacked” with other testosterone-based anabolic steroids. Stanozolol is liked by many due to the fact it causes strength increases without excess weight-gain, promotes increases in vascularity, and will not convert to estrogen. It also does not cause excess water retention, and even sometimes is thought to have a diuretic effect on the body. If you compete at high level an orine test is mandatory. But how scientists find out that you have really used anabolic steroids?
For example, You can read about this specific method: screening for anabolic steroids in doping analysis by liquid chromatography/electrospray ion trap mass spectrometry. This study was published by Biomed Chromatogr. 2006 May;20(5):429-33.
A fast and selective LC/MS/MS method for the screening of four anabolic steroids in human urine has been developed and validated. Liquid-liquid extraction with diethyl ether was applied after enzymatic hydrolysis. Analyses were performed on an ion trap mass spectrometer equipped with electrospray ionisation. MS/MS was applied for all compounds. The analytical run time was 11 min. The LOD for all compounds varied between 1 and 10 ng/mL. Left-over A samples, which were declared positive by GC/MS for the presence of 3′-hydroxystanozolol, were assessed using the described method.
Read more at: PubMed
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