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Anabolic Steroid Stacking Medical Study

May 9, 2006 |

Thinking about anabolic steroid stacking made us compile this article. Read it to learn more about anabolic steroid stacking.

Anabolic steroids have inherent risks, but the main risk here is the improper use of them and worst! the abuse of this kind of substances among our teenagers. The department of biology of the university of Texas at San Antonio examined the effects of stacked anabolic steroids in adolescent male rats.

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Anabolic steroids stacking, in which multiple AAS are taken simultaneously, is commonly employed by humans.

Beginning at puberty gonadally intact male rats received testosterone, nandrolone, or stanozolol. Additional groups received stacked AAS: testosterone + stanozolol, nandrolone + stanozolol, or nandrolone + testosterone. Injections continued during tests for sexual behavior, vocalizations, scent marking, partner preference, aggression and fertility. Body and reproductive tissue weights were taken.

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Sexual and aggressive behaviors were increased by testosterone yet inhibited by stanozolol; nandrolone had no effect. Stacking testosterone with stanozolol prevented the inhibitory effects of stanozolol. Body weight was decreased by testosterone and all stacked AAS. Cell nuclear androgen receptor binding in brain was significantly increased in nandrolone males and decreased in stanozolol males; testosterone males were slightly higher than controls.

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Androgen receptors in stacked groups were intermediate between individual AAS suggesting that stanozolol competed with other AAS for androgen receptors despite its low affinity. The results indicate that stacking AAS influences the effects of individual AAS on behavioral and endocrine measures, and levels of androgen receptor occupation are not directly correlated with AAS effects on behavior.

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