Feb

25

Use Of Stanozolol And Other Steroids - A Case Study

February 25, 2006 |

Bodybuilding Case Study
http://www.exrx.net/Bodybuilding/CaseStudy.html

Concepts:
lbs, lean body, drugs, administrations, competition, Stanozolol, Winstrol, Anadrol, dosage, anabolic-androgenic steroids, exercise, lean body mass, food, weight, body composition, Oxmetholone, mgs.

Summary:
- Prior to competition, bodybuilders typically employ restrictive dietary practices, intense exercise, and the self-administration of pharmaceuticals to reduce body fat and to maintain or gain lean body weight.
- A competitive bodybuilder recorded his nutritional intake, pharmaceutical use, weight training program, body weight, and skin fold measurements while preparing for a state and national bodybuilding event.
- The subject administered a variety anabolic-androgenic steroids in various dosages and combinations.
- In contrast to previous studies, the subject maintained a relatively high caloric diet while incorporating a long duration walking regimen.
- Within this time, the subject won a state competition weighing 226 lbs at approximately 4.2% body fat.
- Few studies have actually attempted to study the effects of diet and anabolic steroids on body composition of a champion bodybuilder before an actual competition.
- The purpose of this study is to document a champion bodybuilder’s precontest preparation practices and to attempt to study their effects on body composition.
- The subject had weight trained steadily for over a decade previous to the state competition except for 2 major breaks.
- The study represented the subject’s fifth cycle of anabolic steroids in his career.
- The same tester took all skinfold measurements since month 80 and throughout the precontest periods using Lange skinfold calipers (Cambridge Scientific Industries, Cambridge, MD).
- The subject recorded all food in his possession at the beginning or one day preceding the period.
- At the end or one day preceding each period, an inventory of the remaining food in the subjects possession was recorded.
- The subject recorded his weight training exercises in a column with a corresponding number indicating the workout weight for that particular exercise.
- When the greater number of the repetition range was final achieved, the workout weight was increased 5%-10%, recorded, and used the following set.
- An attempt was made to administer one or more drugs in a systematic approach throughout the duration of the periods.
- Manipulation in drug type, dosage, and administration pattern was based upon availability of compounds, experimental curiosity, biofeedback, and body composition results.
- For guidance, the subject used the books Underground Steroid Handbook II by Daniel Duchaine (HLR Technical Books, Venice CA) and Anabolic Steroids: What Kind and How Many by Frederick C. Hatfield, Ph.D (Fitness Systems) when planning his cycles.
- The lean body mass gain of 8.9 lbs (.988 lb / day) was undoubtedly due to the introduction of drugs.
- Oxmetholone (Anadrol) was used this period with an average administration of 55.6 mg / Daily for approximately 9 days.
- Beginning two days preceding the period, an average of 62.5 mg of Oxmetholone (Anadrol) was taken for four days.
- Also beginning the same time, 300 mg of Boldenone undecylenate (Equipoise) was administered every week.
- Beginning two days preceding the period, 300 mgs.
- The subject felt and saw no effect after the first week then proceeded to administer 50 mgs of Stanozolol (Winstrol­V) every other day until the end of the period.
- Since fat reduction was not as a great of a concern the last week, the total caloric intake was increased slightly in attempt to allow adequate calories for recovery and increased glycogen stores.
- Resistive training was stopped four days before the show in effort to restore glycogen in the muscle.
- Walking was used more as a means of stress management than fat burning activity the final days before the show.
- Three days before the show, an effort was made to reduce food volume and maintain an elevated caloric intake by eating less more often in order to reduce abdominal circumference caused by intestinal volume.
- Foods containing added salt were discontinued two days before the show in effort to deplete subcutaneous water.
- Approximately six ounces of beer was consumed the evening before the show as to further inhibit Anti­diuretic hormone in effort to deplete subcutaneous water.
- On the morning of the contest, a total body weight of 226 lbs was recorded from a scale used for competition weigh in.
- No other administrations of Winstrol­V or any other drug was taken during this period in anticipation of possible drug testing.
- On the same day, immediately after “weigh-in”, 300 mg of Oxmetholone (Anadrol) was consumed through out the remainder of the day.
- Powerlifters using anabolic steroids have been shown to develop insulin resistance and diminished glucose tolerance (Cohen, 1987).
- Although chronic exercise generally decreases serum insulin levels (Viru, et. al. 1992), this is accompanied by an increase peripheral insulin sensitivity (Richter, 1989).
- Overfeeding has been shown to lead to an increase of lean body mass possibly as a result of increased plasma somatomedin-C, testosterone, and insulin (Forbes, et. al. 1989).
- Insulin can also stimulate the synthesis and storage of cellular protein and glycogen in muscle cells (Di Pasquale, 1993).
- Although insulin’s effect on amino acid uptake into the cell may not be indicative of increased muscle mass (Florini, 1989), insulin may permit maximum protein synthesis to occur in idea physiological situations (Di Pasquale, 1993).
- Anabolic steroids may play a physiological role in the regulation of fatty acid oxidation in liver and fast twitch muscle mitochondria even in the absence of intense physical training (Guzman, 1991).
- The subject attempted to increase muscle mass by a modified carbohydrate load by discontinuing resistive training four days before the show and increasing calories slightly in effort to restore glycogen in the muscle.
- As the cycle progressed, a higher dosage was needed to continue progress.
- Lean body mass gains (4.8 lbs) surpassed all previous losses in lean body mass (-4.1 lbs) with a lower dosage (157.1 mg/day) than the greatest dosage (178.6 mg/day) at period 7.
- 4) A relative decrease of Steroid Binding Hormones due to the previous dosage reduction 5) The relative magnitude of increase from the previous dosage is the greatest of all periods.
- Hurley attempts to dramatizes the dosages of pharmaceuticals used by the athletes by drawing reference to the dose usually administered for androgenic deficiency.
- Their metabolites can be cleared from the body in only fourteen days after discontinuing use and are therefore more commonly used when drug testing is a concern (Yesalis, 1989).
- Submaximal exercise at lower intensities (i.e. 63% maximum oxygen consumption) stimulates lower cortisol response than higher intensities (i.e. 86% maximum oxygen consumption) (Farrell, 1983; Naveri, 1985).

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